Effect of surgical stress on Serum cholesterol level

LP Verma, Chandrakala Dutt, R.D. Dutt

Abstract


Introduction: Stress in the Biological sense is the interaction between damage & defense. Anything that causes stress endangers life unless it is counteracted by adequate adoptive response. Conversely anything endangers life causes stress and adaptive responses. Adaptability and resistance to stress are fundamental requisites for life and very vital organ and function participate in them. Aims: To assess the preoperative value of serum cholesterol in different elective surgical operations. Methodology: In study 40 normal subjects were taken for serum cholesterol estimation. Serum cholesterol was estimated in 100 patients who were taken for various surgeries in respect of age, sex, and social status. The patients were categorized under three groups, group A - patient who underwent operation lasting for 1/2 an hour or less, group B - those with operations lasting between half an hour to 1½ hour, group C - operations lasting for more than 1½ hour. Results: Serum cholesterol value in normal healthy individuals was ranged from 124 to 240. Serum cholesterol level falls to its maximum on the first postoperative day in all cases of group A, B and C except 3 cases in group C in which maximum fall was observed on 3rd postoperative day. Conclusion: The more the surgical stress slower was the recovery.

Full Text:

PDF

References


Biorck G, Blomqvist G, SIEVERS J. Cholesterol values in patients with myocardial infarction and in a normal control group. Acta Med Scand. 1957 Feb 2;156(6):493-7.

Dreyfuss F, Czaczkes JW. Blood cholesterol and uric acid of healthy medical students under the stress of an examination. AMA Arch Intern Med. 1959 May;103(5):708-11.

Frideman M, Rosenman Rh, Carroll V. Changes in the serum cholesterol and blood clotting time in men subjected to cyclic variation of occupational stress. Circulation. 1958 May;17(5):852-61.

Kanter Sl, Goodman Jr, Yarborough J. Determination of free, ester, and total cholesterol without saponification. J Lab Clin Med. 1952 Aug;40(2):303-12.

Kellogg F, Goodman JR. Viscosity of blood in myocardial infarction.Circ Res. 1960 Sep;8:972-9.

Kyle LH, Hess WC, Walsh WP. The effect of ACTH, cortisone and operative stress upon blood cholesterol levels. J Lab Clin Med. 1952 Apr;39(4):605-17.

Man EB, Bettcher PG, Cameron CM, Peters JP. Plasma alpha-amino acid nitrogen and serum lipids of surgical patients. J Clin Invest. 1946 Sep;25(5):701-8.

Peterson JE, Wilcox AA, Haley MI, Keith RA. Hourly variation in total serum cholesterol. Circulation. 1960 Aug;22:247-53.

Thomas CB, Murphy EA. Further studies on cholesterol levels in the Johns Hopkins medical students: the effect of stress at examinations.J Chronic Dis. 1958 Dec;8(6):661-8.

Wertlake PT, Wilcox AA, Haley MI, Peterson JE. Relationship of mental and emotional stress to serum cholesterol levels. Proc Soc Exp Biol Med. 1958 Jan;97(1):163-5.

Desborough JP. Physiological responses to surgery and trauma. In: Hemmings HC Jr, Hopkins PM, eds.Foundations of Anaesthesia. London: Mosby, 1999:713-20.

Jameson P, Desborough JP, Bryant AE, Hall GM. The effect of cortisol suppression on interleukin- 6 and white blood cell responses to surgery.Acta Anaesthesiol Scand. 1997 Feb;41(2):304-8.


Refbacks

  • There are currently no refbacks.