Efficacy of ketamine soaked laryngeal pack in postoperative sore throat after nasal surgeries

Satyendra Uike, Mohammad Ilyas, Ahilya Uike, Sarvesh Jain


Background: Post-operative sore throat (POST) occurs in 21-65% of patients which commonly arises after tracheal intubation and throat packing in patients undergoing general anaesthesia. The aim of the study was to see if ketamine soaked laryngeal pack attenuates POST in postoperative period. Methods: The present study was conducted as a prospective, randomized, double-blind clinical study. After written informed consent, 80 patients belonging to American Society of Anaesthesiologists physical status I-II in the age group 20-50 years, of either sex undergoing nasal surgery under general anaesthesia were enrolled. Patients were randomized into two groups; control group (C) in which laryngeal packing gauge soaked in 5 ml normal saline and group ketamine (K) in which the laryngeal packing gauge soaked in1 ml of ketamine 50 mg (50mg/ ml) with 4.0 ml of normal saline. Incidence and severity of POST was assessed at 0(on reaching post-anaesthesia care unit), 2, 4, 8, 12 and 24 hours post-operatively and graded on a four-point scale (0-3). Results: In present study there was a significant reduction in incidence and attenuation of POST at 0 (on arrival at the post-anaesthetic care unit), 2, 4, 8 hours in postoperative period in ketamine group in comparison to normal saline group. Conclusion: Laryngeal pack soaked in 50 mg ketamine is a simple and effective means in reducing the incidence and severity of postoperative sore throat in patients receiving general anesthesia with endotracheal intubation in nasal surgeries.

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