Perfusion index and Plethysmographic variability index values in spontaneously breathing clinically stable term neonates in room air in the first 10 days of life

J. Ashok Raja, Balasankar S, Mathiarasan K


Background: Perfusion index (PI) and Pleth Variability Index (PVI) are newer pulseoximeter derived numerical non-invasive measures of Peripheral perfusion. PI gives real time changes in peripheral blood flow and PVI the dynamic changes in the PI that occur during the respiratory cycle. Reference values for neonatal population are very few and not yet published for Indian neonates. We undertook this study to establish the reference values for the first 10 days of life in term neonates. Methods: Prospective analytical study conducted at Division of Neonatology, Government Rajaji Hospital, Madurai Medical College. Inborn term neonates, spontaneously breathing in room air and clinically stable, without respiratory distress, on direct breast feeds or oral feeds are eligible for the study. PI, PVI values are recorded on the foot of neonates using Masimo Pulse oximeter for 15 minutes and data transferred to a computer and analyzed. Results: The Primary outcome median value of perfusion index is 1.4 IQR (1.0, 2.0) and Pleth variability index is 19.0 IQR (15.0, 25.0). Conclusions: The reference ranges for perfusion index and pleth variability index in healthy term Indian neonates are presented.

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