Analysis of blood donor deferrals characteristics in a teaching hospital of south India

Zubair Hasan, Seema HS


Context: The health industry today, faces the challenge of safe blood donation. This can be achieved by obtaining blood from voluntary non-remunerated blood donors (VNRD). The rate of deferral has differed from region to region and sometimes in the same region and one centre to another. Aims: 1) To ascertain the chief reasons for blood donation deferral among the blood donors. 2) To study the donor deferral rate and its relation with age and gender. Settings and Design: Descriptive study. Methods and Material: A retrospective study was conducted involving both voluntary and replacement donors who have donated blood to our centre from June 2013 to May 2016.Each donor was selected by a medical officer based on detailed medical history and brief physical examination. Deferral reasons were analysed amongst different categories viz. Gender based (male-female) and various age group categories. Statistical analysis used: Chi square test with significance limit set at 0.05. Results: The total number of donors accepted for blood donation were 1157, out of which 721 were Voluntary donors (62.7%) and 436 were replacement donors (37.3%). Of the total donors who were willing for blood donation, 81 (6.5%) donors were deferred. The donor deferral rate was significantly higher for those above 40 years. Temporary deferrals were commoner among which anaemia was a leading cause. Among permanent deferrals hypertension and jaundice (due to Hepatitis B and Hepatitis C infection) were the common causes. Conclusions: Donor deferral leads to loss of many people from the donation pool to ensure the safety of blood for recipients. Education, motivation, and treatment of these deferred donors due to anemia or other temporary deferrals are important aspects in blood banking, so that these donors may be recruited again.

Full Text:



World Health Organization [internet]. Towards 100% voluntary blood donation . c2010- [cited 2017 Jan 17]. Available from:

Department of AIDS Control Ministry of Health and Family Welfare Government of India [internet]. Annual report:2008- 2009 pg 27 [cited 2017 Jan 17]. Available from: NACO_2008-09.pdf.

Annual Action Plan. Karnataka State AIDS Prevention Society; 2010-2011. p. 129.

World Health Organization [internet]. Blood donor selection and counseling.c2012-[cited 2017 Jan 17]. Available from:

Zou S, Eder AF, Musavi F, Notari EP, Fang CT, Dodd RY, et al. Implementation of the uniform donor history questionnaire across the American Red Cross Blood Services: Increased deferral among repeat presenters but no measurable impact on blood safety. Transfusion 2007;47:1990-8.

AABB. Standards for Blood Banks and Transfusion Services. 26th ed. Bethesda: American Association of Blood Banks; 2009.

Chenna D, Shastry S, Murugesan M, Baliga PB. Implication of deferral pattern on the donor pool: Study at a Tertiary Care Hospital. J Appl Hematol 2015;6:111-4.

Sawanpanyalert P, Uthaivoravit W, Yanai H, Limpakarnjanarat K, Mastro TD, Nelson KE. Donation deferral criteria for human immunodeficiency virus positivity among blood donors in northern Thailand. Transfusion. 1996;36:242–9.

Galea G, Gillon J, Urbaniak SJ, Ribbons CA. Study on medical donor deferrals at sessions. Transfus Med. 1996 Mar;6(1):37-43.

Halperin D, Baetens J, Newman B. The effect of short-term, temporary deferral on future blood donation. Transfusion. 1998 Feb;38(2):181-3.

Naveen Agnihotri. Whole blood donor deferral analysis at a center in Western India.Asian J Transfus Sci.2010; 4(2):116-122.

Alok K, Satyendra P, Sharma SM, Ingole NS, Gangane N. Impact of counseling on temporarily deferred donor in a tertiary care hospital, central India: A prospective study.Int J Med Public Health 2014;4:400-3.

Talonu T. Causes of volunteer blood donor rejection in Papua New Guinea. P N G Med J. 1983 Sep-Dec;26(3-4):195-7.

Nagarekha Kulkarni. Analysis of donor deferral in blood donors. Journal of Evolution of Medical and Dental Sciences 2012;1(6):1076-1082

Unnikrishnan B, Rao P, Kumar N, Ganti S, Prasad R et al. Profile of blood donors and reasons for deferral in coastal South India. Australasian Medical Journal. 2011; 4(7):379-385.

Sundar P, Sangeetha SK, Seema DM, Marimuthu P, Shivanna N. Pre-donation deferral of blood donors in South Indian set-up: An analysis. Asian J Transfus Sci. 2010 Jul;4(2):112-5. doi: 10.4103/0973-6247.67037.

Zou S, Musavi F, Notari EP, Rios JA, Trouern-Trend J, Fang CT. Donor deferral and resulting donor loss at the American Red Cross Blood Services, 2001 through 2006. Transfusion. 2008 Dec;48(12):2531-9. doi: 10.1111/j.1537-2995.2008.01903.x. Epub 2008 Aug 20.

Chaudhary RK, Gupta D, Gupta RK. Analysis of donor-deferral pattern in a voluntary blood donor population. Transfus Med. 1995 Sep;5(3):209-12.

William R, Matthew S, McCullough J. The Unite States’ potential blood donor pool: estimating the prevalence of donor-exclusion factors on the pool of potential donors. Transfusion 2007; 47(7): 1180-88.

Garry PJ, VanderJagt DJ, Wayne SJ, Koehler KH, Rhyne RL, Simon TL. A prospective study of blood donations in healthy elderly persons. Transfusion. 1991 Oct;31(8):686-92.

Custer B, Johnson ES, Sullivan SD, Hazlet TK, Ramsey SD, Hirschler NV, Murphy EL, Busch MP. Quantifying losses to the donated blood supply due to donor deferral and miscollection. Transfusion. 2004 Oct;44(10):1417-26.

Bahadur S, Jain S, Goel RK, Pahuja S, Jain M. Analysis of blood donor deferral characteristics in Delhi, India. Southeast Asian J Trop Med Public Health 2009;40:1087-91.

Mollison PL. Blood Transfusion in Clinical Medicine. 3rd Edition.Massachusetts: Blackwell Scientific Publications; 1961.

Ranveet Kaur, Sabita Basu, Neelam Marwaha . A reappraisal of underlying causes in donor deferral. Ann Natl Acad Med Sci. 2002; 38:93-9.

Charles KS, Hughes P, Gadd R, Bodkyn CJ, Rodriquez M. Evaluation of blood donor deferral causes in the Trinidad and Tobago National Blood Transfusion Service. Transfusion Med 2010; 20(1):11-14.


  • There are currently no refbacks.