Prevalence and antibiotic susceptibility pattern of Escherichia coli isolated from urine samples in patients attending a tertiary care hospital, Chennai

Lakshmi K, Aishwarya J.R, Sharanya K, Sindhu Cugati, Chitralekha S


Background: Escherichia coli (E.coli)is one of the commonest cause of urinary tract infections. The drug resistance to many of the common antibiotics in use, has been alarming in the urinary E. coli isolates. Objective: To study the prevalence of E.coli in urinary tract infections and to study their antibiotic susceptibility pattern of the isolates. Material and Methods: This study was conducted in a tertiary care hospital in Chennai over a period of 4 months. A total of 3408 urine samples were processed for bacterial culture using standard methods. E.coli isolates were further confirmed by standard microbiological and biochemical methods. Antibiotic susceptibility of the E.coli isolates were carried out by Kirby Bauer disc diffusion method. Results: A total of 102 E.coli isolates were obtained from the urine specimen and were screened for the antibiotic susceptibility pattern. E.coli isolates were highly susceptible to imipenem (100%) and nitrofurantoin (96%). High degree of resistance was seen to antibiotics like ampicillin, amoxycillin clavulanic acid, cefazolin and cotrimoxazole,ciprofloxacin and cefotaxime. Conclusion: Our results give the data about the antibiotic susceptibility pattern of the Escherichia coli isolates in this locality. This will help in the choice of the appropriate antibiotics for treatment of the infections.

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