Significance of platelet indices in burns patient

Sofiya C, B. Pushpa


Introduction: Burns constitute an important health concern all over the world. The main aim of burns treatment is reducing morbidity and mortality. Platelet count was proved to be an important prognostic index in burns. The main aim of this study is to find the significance of other Platelet indices in burns patient. Methods: This study was conducted in a Tertiary care Hospital in Chennai for a sample size of 143 burns patients. Patients were divided into two groups based on the Total burn surface area (Group A with <30% Total Burns Surface Area and group B with >30% Total Burn Surface area). Normal persons with similar ages are taken as Control. Platelet indices were analysed for these patients on the day of admission and on the fourth day of admission using Sysmex 5-part analyser. BAUX score was also calculated for the Burns patient. The results were compared between platelet indices, clinical parameters and Baux score among different groups. Results: The results of platelet indices between group A, group B and control group were compared. In group A, no significant change in platelet indices was observed. But in group B, the mean value of Platelet count decreases from 217 on the day admission to 164 on the fourth day of admission and the Mean Platelet Volume increases from 9.88 on the day of admission to 10.54 on the fourth day of admission. Mean Platelet Volume also correlates linearly with BAUX score. Conclusion: BAUX score is a prognostic scoring system in which higher value indicates poorer prognosis. MPV correlates linearly with BAUX score which indicates raising MPV act as poor prognostic factor. Platelet indices which can be analyzed with simple automated analyser can act as important prognostic factor in burns patient which helps in deciding appropriate treatment at appropriate time.

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Mock C, Peck M, Peden M, Krug E, eds. A WHO plan for burn prevention and care. Geneva, World Health Organisation, 2008.

Osler T, Glance LG, Hosmer DW. Simplified estimates of the probability of death after burn injuries: extending and updating the baux score. J Trauma. 2010 Mar; 68(3):690-7. doi: 10.1097/TA.0b013e3181c453b3.

Gupta JL, Makhija LK, Bajaj SP. National programme for prevention of burn injuries. Indian J Plast Surg. 2010 Sep; 43 (Suppl): S6-S10. doi: 10. 4103 / 0970-0358.70716.

Yastı AÇ, Şenel E, Saydam M, Özok G, Çoruh A, Yorgancı K. Guideline and treatment algorithm for burn injuries. Ulus Travma Acil Cerrahi Derg. 2015 Mar;21 (2): 79-89. doi: 10.5505/tjtes.2015.88261.

Rowan MP, Cancio LC, Elster EA, Burmeister DM, Rose LF, Natesan S, Chan RK, Christy RJ, Chung KK. Burn wound healing and treatment: review and advancements. Crit Care. 2015 Jun 12;19:243. doi: 10. 1186/ s13054-015-0961-2.

Marina Pavic, Lara Milevoj. Platelet count monitoring in burn patients. Biochemia Medica 2007;17 (2): 212-9. doi:10.11613/BM.2007.021.

Shehan Hettiaratchy, Peter Dziewulski., Patho-physiology and types of Burns, ABC of Burns., BMJ,vol 328 (2004)-1427-1429.

Kao CC, Garner WL. Acute burns. Plast Reconstr Surg 2000;105:2482-92.

Sarda DK, Dagwade AM, Lohiya S, et al. Evaluation of platelet count as a prognostic indicator in early detection of post burn septicemia. Bombay Hosp J. 2005; 47(3):3-6.

Weyrich AS, Lindemann S, Zimmerman GA. The evolving role of platelets in inflammation. J Thromb Haemost. 2003 Sep;1(9):1897-905.

Summer GJ, Romero-Sandoval EA, Bogen O, Dina OA, Khasar SG, Levine JD. Proinflammatory cytokines mediating burn-injury pain. Pain. 2008 Mar;135(1-2): 98-107. Epub 2007 Jun 27.

Jun Hur, Hyeong Tae Yang, Hyun Soo Kim. Infammatory cytokines and their prognostic ability in cases of Major Burn injury. Ann Lab Med. 2015 Jan; 35 (1): 105-110. doi:10.3343/alm.2015.35.1.105.

Armen Yuri Gasparyan, Aamer Sandoo et al. Mean Platelet volume in patients with Rheumatoid arthritis: the effect of anti-TNF alpha therapy. Rheumatology International, Springer Verlag, 2010, 30(8), pp1125-1129. doi: 10.1007/s00296-009-1345-1.

Maqsood, Muhammad Haisum & Khan. Platelet aggregation: Prognostic Marker in Burn survival. Annals of King Edward Medical University. 2016; Vol 22(2): 152-154.

Ashok Surybhanji Gajbhiye, M.M.Meshram et al. Platelet count as a Prognostic Indicator in Burn Septicemia. Indian J Surg. 2013 Dec; 75(6): 444-448. doi: 10.1007/s12262-012-0532-6.

Sadiye, Nesrin et al. Mean Platelet volume levels in Patients with burn injury. Indian Journal of Research. August 2013; 2(8): 187-90.


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