Clinico-pathological review of ciliated muconodular papillary tumour of lung

Sabah Nayef Nemri, Nazima Haider, Sohaila Fatima


Pulmonary tumours with cilia formation are rare and are usually recognized as benign. Ciliated muconodular papillary tumour (CMPT) of lung is a rare entity recently described in 2002. It is characterized by the presence of papillary tumour consisting of ciliated columnar, goblet, and basal cells. Although most of its features are of a benign tumour, some histological characteristics do suggest low-grade malignancy. We describe a case of CPMT in a 36 year old male.

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Ishikawa Y. Ciliated muconodular papillary tumor of the peripheral lung: benign or malignant. Pathol. Clin. Med. (Byouri-to-Rinsho) 2002; 20 : 964–965.(In Japanese)

Ishikawa M, Sumitomo S, Imamura N, Nishida T, Mineura K, Ono K. Ciliated muconodular papillary tumor of the lung: report of five cases. Journal of Surgical Case Reports 2016; 8:1–4.doi: 10.1093/jscr/ rjw144

Flieder DB, Thivolet-Bejui F, Popper H. Tumor of the lung. Benign epithelial lesions. In: Travis WD, Brambilla E, Mu¨ller-Hermelink HK, Harris CC, editors. World Health Organization classification of tumors: pathology and genetics of tumors of the lung, pleura, thymus and heart. Lyon:IARC Press2004:78–81.

Nakamura S, Koshikawa T, Sato T, Hayashi K, Suchi T. Extremely well differentiated papillary adenocar-cinoma of the lung with prominent cilia formation. Pathol. Int. 1992;42 (10):745–750.

Kamata T, Yoshida A, Kosuge T, Watanabe S, Asamura H, Tsuta K. Ciliated muconodular papillary tumors of the lung: a clinicopathologic analysis of 10 cases. Am J SurgPathol 2015; 39(6):753–60.doi: 10. 1097/ PAS.0000000000000414.

Lau KW, Aubry MC, Tan GS, Lim CH, Takano AM. Ciliated muconodular papillary tumor: a solitary peripheral lung nodule in a teenage girl. Hum Pathol 2016Mar; 49:22-6. doi: 10.1016/j.humpath.2015.09.038

Sato T, Koike K, Homma A, Yokoyama A. Ciliated muconodular papillary tumour of the lung: a newly defined low-grade malignant tumour. Interact Cardiovasc Thorac Surg 2010; 11(5): 685–687.doi: 10. 1510/ icvts. 2009.229989.

Arai Y, Shimizu S, Eimoto T, Shimizu I, Otsuki Y, Kobayashi H, Travis WD. Peripheral pulmonary papillary / glandular neoplasms with ciliated cells and a component of well-differentiated adenocarcinoma: report of three tumours. Histopathology 2010; 56 (2): 265–269. doi: 10.1111/j.1365-2559.2009.03463.x


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