Cervical lymph node FNAC: a simple and sensitive tool to diagnosis malignancies

Majal G. Shah, Deepak K. Goel, Trupti S. Patel, Priti P. Trivedi

Abstract


Introduction: Fine needle aspiration cytology (FNAC) of a lymph node is a simple screening and diagnostic tool to diagnose malignancies both primary as well as secondary which not only confirms the presence of metastatic disease, but also suggests regarding the nature and origin of the primary tumour. It is a well-tolerated, cost effective, almost free of complication procedure and reproducible which helps to diagnose and monitor the recurrence of malignancies. Aim: To assess the various malignant causes of cervical lymphadenopathy through FNAC. Design: A retrospective record based cross-sectional study of 125 patients with enlarged cervical lymph nodes diagnosed to have primary or secondary lymph node malignancy by cytology and confirmed by histopathology and immunohistochemistry wherever required. Materials and Methods: The material was obtained from patients, having enlarged cervical neck node over a period of one year in cytology laboratory of the Department of Pathology, Gujarat cancer research institute.  Cervical lymph nodes were aspirated, and smears were prepared & processed following standard techniques. Data was collected, tabulated and then analysed. Results: In this study,125 cases of cervical lymphadenopathy were analysed. Male were affected much more commonly than females in the ratio of approximately 9:1. The most common age of presentation was fifth and the sixth decade. Most common malignancy to be diagnosed was squamous cell carcinoma. Most common primary site was oral cavity. Conclusion: FNAC is a quick, convenient  and  safe  method  for diagnosis of suspected / unsuspected metastatic and recurrence of malignancy in neck nodes.

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References


Khajuria R, Goswami KC, Singh K, Dubey VK. Pattern of lymphadenopathy on fine needle aspiration cytology in Jammu. JK Sci. 2006;8(3):145-149.

Hirachand S, Lakhey M, Akhter J, Thapa B. Evaluation of fine needle aspiration cytology of lymph nodes in Kathmandu Medical College, Teaching hospital. Kathmandu Univ Med J (KUMJ). 2009;7 (26): 139-142.

Ahmad T, Naeem M, Ahmad S, Samad A, Nasir A. Fine needle aspiration cytology (FNAC) and neck swellings in the surgical outpatient. J Ayub Med Coll Abbottabad. 2008;20(3):30-32.

Paul PC, Goswami BK, Chakrabarti S, Giri A, Pramanik R. Fine needle aspiration cytology of lymph nodes-An institutional study of 1448 cases over a five-year period. J Cytol. 2004;21(4):187.

Bhattacharjee A, Chakraborty A, Purkaystha P. Prevalence of head and neck cancers in the north east—an institutional study. Indian Journal of Otolaryngology and Head and Neck Surgery. 2006; 58(1):15-19. doi: 10.1007/BF02907731

Mehrotra R, Singh M, Gupta RK, Singh M, Kapoor AK. Trends of prevalence and pathological spectrum of head and neck cancers in North India. Indian J Cancer. 2005; 42(2): 89-93. doi: 10.4103/0019-509X. 16698

Engzell U, Jakobsson PA, Sigurdson A, Zajicek J. Aspiration biopsy of metastatic carcinoma in lymph nodes of the neck. A review of 1101 consecutive cases. ActaOtolaryngol. 1971;72(1):138-147.doi:10.3109/ 000 16487109122466

Ustün M, Risberg B, Davidson B, Berner A. Cystic change in metastatic lymph nodes: a common diagnostic pitfall in fine-needle aspiration cytology. Diagn Cytopathol. 2002;27(6):387-392. doi:10.1002/dc. 10201

Bagwan IN, Kane SV, Chinoy RF. Cytologic evaluation of the enlarged neck nodes. FNAC utility in metastatic neck disease. Int J Pathol. 2007;6(2).

Konar K, Ghosh S, Ghosh T, Bhattacharya S, Sanyal S. Pitfalls in the cytodiagnosis of metastatic squamous cell carcinoma in the head and neck: A retrospective study. J Cytol. 2008;25(4):119-122.

Afroz, M., Akhtar, N., Siddiquee, B. Metastatic neck node - a clinical study of 60 cases. Bangladesh Journal of Otorhinolaryngol. 2009;15(1):26-30. doi: https://doi.org/10.3329/bjo.v15i1.4307

Alam K, Khan A, Siddiqui F, Jain A, Haider N, Maheshwari V. Fine needle aspiration cytology (FNAC), a handy tool for metastatic lymphadenopathy. Int J Pathol. 2010;10(2):1-7.

Khajuria R, Goswami KC, Singh K, Dubey VK. Pattern of lymphadenopathy on fine needle aspiration cytology in Jammu. JK Sci. 2006;8(3):145-149.

Alam K, Maheshwari V, Haider N, Siddiqui F, Jain A, Khan A. Fine needle aspiration cytology (FNAC), a handy tool for metastatic lymphadenopathy. Int J Pathol. 2009;10(2).

Hsu C, Leung BS, Lau SK, Sham JS, Choy D, Engzell U. Efficacy of fine‐needle aspiration and sampling of lymph nodes in 1,484 chinese patients. Diagnostic Cytopathol. 1990;6(3): 154-159.

H. Kumar, S.S. Chandanwale, C.R. Gore, A.C. Buc, V. H. Satav, P.M. PagaroRole of fine needle aspiration cytology in assessment of cervical lymphadenopathy. Med J DY Patil Univ.2013;6(4):400-404. doi: 10. 4103/ 0975-2870.118287


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